Vascular Dysfunction in Horses with Endocrinopathic Laminitis

Vascular Dysfunction in Horses with Endocrinopathic Laminitis

Endocrinopathic laminitis (EL) is a vascular condition of the equine hoof resulting in severe lameness with both welfare and economic implications. EL occurs in association with equine metabolic syndrome and equine Cushing's disease. Vascular dysfunction, most commonly due to endothelial dysfunction, is associated with cardiovascular risk in people with metabolic syndrome and Cushing's syndrome...

The Prevalence and Histopathology of Endocrinopathic Laminitis in Horses

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Endocrinopathic laminitis in the horse

Endocrinopathic Laminitis, Obesity-Associated Laminitis, and Pasture-Associated Laminitis

In a recent online survey, we asked equine practitioners to list the three most common causes of laminitis in horses seen within their practice. We expected veterinarians to list colitis, colic, and retained placenta as the primary causes of laminitis, but many respondents listed obesity, insulin resistance (IR), equine metabolic syndrome (EMS), pituitary pars intermedia dysfunction (PPID), and...

The pharmacologic basis for the treatment of endocrinopathic laminitis.

Although the treatment and management of laminitis in the horse requires a holistic and often multidisciplinary approach from the veterinarian, farrier, and nutritionist, this review focuses on pharmacologic interventions that might have prophylactic benefit, specifically in the horse with laminitis as a result of pituitary pars intermedia dysfunction and equine metabolic syndrome.